Competitive repopulation in unirradiated normal recipients [editorial; comment]

Competitive repopulation in unirradiated normal recipients.

Editorial Comment: Therapeutic Orphans

By an odd and unfortunate twist of fate, infants and children are becoming “therapeutic or pharmaceutical orphans.”1 Since 1962 they have been denied the use of many new drugs. The Drug Laws of 1962 had their inception following a pediatric tragedy—the thalidomide catastrophe. The laws of 1938 followed another which resulted from the use of a pediatric dosage form, “elixir” of sulfanilamide. By...

Editorial comment: The Nuss procedure.

the quality of life in young male adults with pectus excavatum deformity. Nakajima T. Stress distribution on the thorax after the Nuss procedure for pectus excavatum results in different patterns between adult and child patients. Postoperative consumption of opioid analgesics following correction of pectus excavatum is influenced by pectus severity: a single-centre study of 236 patients undergo...

EDITORIAL COMMENT Outcomes in Diabetics Undergoing Revascularization

Diabetes mellitus, a major determinant of cardiovascular events, portends an adverse prognosis in patients with coronary artery disease regardless of treatment strategy. Among patients undergoing coronary revascularization procedures, the Bypass Angioplasty Revascularization Investigation (BARI) trial (1) demonstrated an unfavorable interaction between diabetes and an initial strategy of percut...

Reply to the editorial comment from Van der Wall concerning ‘The right ventricle: always normal in normal subjects?’

Right ventricular (RV) structure and function serve as important indicators of a wide spectrum of heart diseases such as congenital heart disease, pulmonary hypertension, hypertro-phic cardiomyopathy and arrhythmogenic right ventricular cardiomyopathy/disease (ARVC/D) [1–3]. Over the past years cardiac magnetic resonance imaging (CMR) has proven itself as the preferred imaging modality of choic...